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KMID : 1225720150070020186
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Allergy, Asthma & Immunology Research : AAIR
2015 Volume.7 No. 2 p.186 ~ p.189
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Butter Tolerance in Children Allergic to Cow’s Milk
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Yanagida Noriyuki
Minoura Takanori
Kitaoka Setsuko
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Abstract
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We performed an oral food challenge (OFC) with 10 g of butter (equivalent of 2.9 mL cow’s milk) and 25-mL heated cow’s milk for 68 children with cow’s milk-allergy. Thirty-eight children reacted only to heated cow’s milk. Twenty-four children reacted to neither heated milk nor butter. Thirty-eight (86.4%) of 44 patients with positive results to the OFC for heated milk could safely tolerate butter. It is highly likely that even children with cow’s milk-allergy who show positive results to an OFC for heated milk can consume butter. The milk-specific IgE value indicative of a negative predictive value of over 95% was 17.8 kUA/L, and patients with low milk-specific IgE values may be able to safely consume butter. Including butter in the diets of patients with milk-allergy after a butter challenge may improve quality of life.
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KEYWORD
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Food hypersensitivity, butter, milk, probability
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